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David L. Harmon, Ph. D.
Professor, Beef Coordinator. Ruminant
Nutrition; Digestive Physiology
Director of Graduate Studies
Department of Animal Sciences
University of Kentucky
814 W.P. Garrigus Bldg
Lexington, KY 40546
Telephone: (859) 257-7516
FAX: (859) 257-3412
E-mail: dharmon@uky.edu
EDUCATION
Ph.D., University of Nebraska-Lincoln
Major: Animal Science (Ruminant Nutrition); 1980-1983
Dissertation topic: D(-) lactate metabolism in beef cattle
Major advisor: Dr. R. A. Britton
M.S., University of Nebraska-Lincoln
Major: Animal Science (Ruminant Nutrition); 1978-1980
Thesis topic: Acidosis, lactate and mineral metabolism
associated with high concentrate feeding
Major advisor: Dr. R. A. Britton
B.S., The Ohio State University
Major: Nutrition, 1974-1978
EXPERIENCE
Department of Animal Science and Industry,
Kansas State University
August 1983 -February 1989, Assistant Professor
Appointment .6 Research - .4 Teaching
February 1989 - December 1991, Associate Professor
Department of Animal Sciences, University of Kentucky
January 1992 - present, Associate Professor
Appointment .75 research - .25 Teaching
July 1995 - present, Professor
Teaching
Laboratory Methods in the Nutritional
Sciences, Graduate lecture and laboratory. Advanced Ruminant
Nutrition, Graduate lecture. Experience with graduate
and undergraduate courses.
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Fundamentals of Nutrition, Introductory
undergraduate nutrition. |
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Animal Nutrition, Graduate, nutritional
physiology and metabolism. |
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Analytical Techniques in Animal
Science, Graduate laboratory methods. |
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Radioisotopes and Radioimmunoassay,
Graduate laboratory methods. |
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Techniques in Animal Nutrition
Research, Graduate lecture and laboratory. |
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Advanced Ruminant Nutrition, Graduate
lecture. |
Additional Activities
IACUC College of Agriculture Subcommittee
Chair (1997-present) Chair, Director of Graduate Studies
(2002-Present)
Research
Research program has dealt with identifying
relationships between diet digestion, gut metabolism and
nutrient absorption in ruminants. The major objectives
are:
Proficiency in a variety of surgical
techniques for nutrition studies.
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Ruminal, duodenal, ileal and esophageal
cannulations. |
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Hepatic, portal and arterial catheterizations.
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- cannulation.
Experience with in vivo and in vitro use of metabolic
tracers. |
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Use of tissues for in vitro metabolic
studies. |
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In vivo measurement of nutrient
flux and absorption. Proficient with most laboratory
equipment and analyses. |
Additional Activities
Member of University Animal Care Use
and Committee (KSU and UK) IACUC College of Agriculture
Subcommittee Chair (1997-present) Chair, Beef commodity
group UK (1993-present)
AFFILIATIONS AND HONORS
American Society of Animal Science
Director at Large 1999-2002
American Society of Animal Science
AFIA Ruminant Nutrition Award- 1998
Journal of Animal Science-Section
Editor Ruminant Digestion and Metabolism - 1992-1995
Midwest American Society of Animal
Science Young Researcher Award - 1992
American Institute of Nutrition
American Society of Animal Science
Gamma Sigma Delta
Sigma Xi
Widaman Trust Outstanding Graduate
Student Award, 1982.
Recent Publications
Huntington,
G.B., D.L. Harmon, and C.J. Richards.
Sites, rates, and limits of starch digestion and glucose
metabolism in growing cattle. Journal of Animal Science
84:E14-E24. 2006.
Huntington,
G.B., D.L. Harmon, N.B. Kristensen, K.C.
Hanson, and J.W. Spears. Effects of a slow-release urea
source on absorption of ammonia and production of urea
by cattle. Animal Feed Science and Technology 130:225-241.
2006.
Kitts, S.E.,
D.L. Harmon, E.S. Vanzant, and K.R. McLeod.
Effects of chlortetracycline (CTC) and Revalor-S on the
growth performance and carcass quality traits of finishing
beef steers. Journal of Animal and Veterinary Advances
5: 70-76. 2006.
Mouro, G.F.,
A.F. Branco, D.L. Harmon, F.J. Maia,
S.M. Coneglian, and T.F.M. Ribeiro. Fontes de carboidratos
e ionoforo em dietas contendo oleo vegetal para ovinos:
digestibilidade, balanco de nitrogenio e fluxo portal
de nutrients. Revista Brasileira de Zootecnia 35: 2144-2153.
2006.
Yamka, R.M.,
D.L. Harmon, W.D. Schoenherr, C. Khoo,
K.L. Gross, PhD; S.J. Davidson, and D.K. Joshi. In vivo
measurement of flatulence and nutrient digestibility in
dogs fed poultry by-product meal, conventional soybean
meal, and low-oligosaccharide low-phytate soybean meal.
American Journal of Veterinary Research 67:88-94. 2006.
Kristensen,
N.B., G.B. Huntington and D.L. Harmon.
Splanchnic carbohydrate and energy metabolism in growing
ruminants. pp. 405-432. In: Biology of Growing Animals
Series. Biology of Metabolism in Growing Animals. D.G.
Burrin and H. J. Mersman (Eds.). Elsevier, Boston. 2005.
Yamka,
R.M., U. Jamikorn, A.D. True and D.L. Harmon.
Evaluation of low-ash poultry meal as a protein source
in canine foods. Journal of Animal Science 81:2279-2284.
2003.
Yamka, R.M.,
U. Jamikorn, A.D. True and D.L. Harmon.
Evaluation of soybean meal as a protein source in canine
foods. Animal Feed Science Technology 109:121-132. 2003.
Swanson, K.C., J.C. Matthews, C.A.
Woods and D.L. Harmon. Influence of substrate
and/or neurohormonal mimic on in vitro pancreatic enzyme
release from calves post-ruminally infused with partially
hydrolyzed starch and/or casein. Journal of Animal Science
81:1323-1331. 2003.
Richards, C.J., K.C. Swanson, S.J.
Lewis, D.L. Harmon and G.B. Huntington.
Pancreatic exocrine secretion in steers infused post-ruminally
with casein and cornstarch. Journal of Animal Science
81:1051-1056. 2003.
Swanson,
K.C., J.C. Matthews, C.A. Woods, and D.L. Harmon.
2002. Post-ruminal administration of partially hydrolyzed
starch and casein influences pancreatic α-amylase
expression in calves. Journal of Nutrition 132:376-381.
Akay,
V., J.A. Jackson Jr., and D.L. Harmon. 2002. NutriDense
and waxy corn hybrids: Effects on site and extent of disappearance
of nutrients in sheep. Journal of Animal Science 80:1335-1343.
Harmon, D.L., C.J. Richards, K.C. Swanson, J.A. Howell,
J.C. Matthews, G.B. Huntington, A.D. True, S. Gahr, and
R.W. Russell. 2001. Influence of ruminal or postruminal
starch on visceral glucose metabolism in steers. pp. 273-276.
IN: A. Chwalibog and K. Jakobsen, eds. Energy Metabolism
in Animals. Proceedings,15th International
Symposium on Energy Metabolism, Snekkersten, Denmark.
Wageningen Pers, Wageningen, the Netherlands.
Harmon, D.L., and K.R. McLeod. 2001. Glucose uptake
and regulation by intestinal tissues: Implications and
whole-body energetics. Jour-nal of Animal Science, 79:E59-E72.
Harmon, D.L., C.J. Richards, K.C. Swanson, J.A. Howell,
J.C. Matthews, A.D. True, G.B. Huntington, S.A. Gahr,
and R.W. Russell. 2001. Influence of ruminal or
postruminal starch on visceral glucose metabolism in steers.
EAAP Publication No. 103. pp. 273- 276. Proceedings, 15th
International Symposium on Energy Me-tabolism, Snekkersten,
Denmark.
Howell,
J.A., A.D. Matthews, K.C. Swanson, D.L. Harmon,
and J.C. Matthews. 2001. Molecular Identification of high-affinity
glutamate transporters in sheep and cattle forestomach,
intestine, liver, kid-ney, and pancreas. Journal of Animal
Science, 79:1329-1336.
McLeod,
K.R., R.L. Baldwin VI, D.L. Harmon, C.J. Richards,
and W.V. Rumpler. 2001. Influence of ruminal and postruminal
starch infu-sion on energy balance in growing steers.
EAAP Publication No. 103. pp. 217-220. Proceedings, 15th
International Symposium on Energy Metabolism, Snekkersten,
Denmark.
Bauer,
M.L., D.L. Harmon, D.W. Bohnert, A.F. Branco, and
G.B. Huntington. 2001. Influence of α-linked glucose
on sodium-glucose cotransport activity along the small
intestine in cattle. Journal of Animal Science, 79:1917-1924.
Swanson, K.C., J.C. Matthews, A.D.
Wilson, J.A. Howell, C.J. Richards, and D.L. Harmon.
2000. Influence of dietary carbohydrate source and energy
intake on pancreatic alpha amylase expression in lambs.
J. Nutr. 130:2157-2165.
Swanson, K.C., D.L. Harmon,
K.A. Jacques, B.T. Larson, C.J. Richards, D.W. Bohnert
and S.J. Lewis. 2000. Efficacy of chromium yeast for growing
beef steers. Anim. Feed Sci. Technol. 86:95-105.
Strickling, J. A.,
D.L. Harmon ,K.A. Dawson and K.L. Gross.
2000. Evaluation of oligosaccharide addition to dog diets:
influences on nutrient digestion and microbial populations.
Anim. Feed Sci. Technol. 86:205-219.
Silvio, J., D.L.
Harmon, K. L. Gross, and K. R. McLeod. 2000. Influence
of fiber fermentability on nutrient digestion in the dog.
Nutrition. 16:289-295.
Ludden, P. A., D.
L. Harmon, B. T. Larson and D. E. Axe. 2000. Influence
of the novel urease inhibitor N-(n-butyl) thiophosphoric
triamide (NBPT) on ruminant nitrogen metabolism. 1. In
vitro urea kinetics and substrate digestion. J. Anim.
Sci. 78:181-187.
Ludden, P. A., D.
L. Harmon, G. B. Huntington, B. T. Larson,and D. E.
Axe. 2000. Influence of the novel urease inhibitor N-(n-butyl)
thiophosphoric triamide (NBPT) on ruminant nitrogen metabolism.
2. Ruminal nitrogen metabolism, diet digestibility, and
nitrogen balance in lambs. J. Anim. Sci. 78:188-198.
Bohnert, D. W, D.
L. Harmon , B. T. Larson, C. J. Richards, and M. N.
Streeter. 2000. Efficacy of laidlomycin propionate in
low-protein diets fed to growing beef steers: effects
on steer performance and ruminal nitrogen metabolism.
J. Anim. Sci. 78:173-180.
Bohnert, D.W., B.T.
Larson, S.J. Lewis, C.J. Richards, K.C. Swanson, D.L.
Harmon and G.E. Mitchell, Jr. 1999. Net nutrient flux
by visceral tissues of lambs fed diets differing in supplemental
nitrogen source. J. Anim. Sci. 77:2545-2553.
Branco, A.F., D.L.
Harmon, D.W. Bohnert, B.T. Larson and M.L. Bauer.
1999. Estimating true digestibility of carbohydrate in
the small intestine of steers. J. Anim. Sci. 77:1889-1895.
Larson, B.T., D.L.
Harmon, L.P. Bush, E.L. Piper and L.M. Griffis. 1999.
Alkaloid binding and activation of D2 dopamine
receptors in cell culture. J. Anim.
Sci. 77:942-947.
Harmon,
D.L., J.A. Walker, J.M. Silvio, A.M. Jamikorn and
K.L. Gross. 1999. Nutrient digestibility in dogs fed fiber-containing
diets. Vet. Clin. Nutr. 6:6-10.
ABSTRACTS
Huntington,
G.B., C. Richards and D. Harmon. Sites,
rates and limits of carbohydrate digesiton and glucose
metabolism in growing cattle. Journal of Animal Science
83:(Suppl. 1) 72. 2005.
Taylor, C.C.,
N.A. Elam, S.E. Kitts, K.R. McLeod, D.E. Axe and D.L.
Harmon. Influence of slow-release urea on nitrogen
balance and nutrient absorption of steers. Journal of
Animal Science 83:(Suppl. 1) 321. 2005.
Speight, S.M.
and D.L. Harmon. Application of carbohydrase
inhibitors to moderate rumen fermentation: In vitro evaluation.
Journal of Animal Science 83:(Suppl. 1) 307. 2005.
Huntington,
G.B., C. Richards and D. Harmon. Sites,
rates and limits of carbohydrate digesiton and glucose
metabolism in growing cattle. Journal of Animal Science
83:(Suppl. 1) 72. 2005.
Elam, N.A.,
C. Taylor, S.E. Kitts, K.R. McLeod, D.L. Harmon
and E.S. Vanzant. Quantitative assessment of visceral
energy metabolism in beef steers consumed graded levels
of forage. Journal of Animal Science 83:(Suppl. 1) 52.
2005.
Rodriguez,
S.M., K.C. Guimaraes, J.C. Matthews, K.M. McLeod, R.L.
Baldwin and D.L. Harmon. Influence of
abomasal carbohydrate on small intestinal sodium-dependent
glucose co-transporter activity in steers. Journal of
Animal Science 81(Suppl. 1):266. 2003.
Yamka, R.M.,
K.R. McLeod. D.L. Harmon, H.C. Freetly
and W.D. Schoenherr. Accounting for the proportion of
alpha-amino nitrogen in crude protein improves metabolizable
energy prediction in dry extruded dog foods. Journal of
Animal Science 81(Suppl. 1):260. 2003.
Fisher, M.J.,
D.W. Bohnert, C.J. Ackerman, C.S. Schauer, T. DelCurto,
A.M. Craig, E.S. Vanzant, D.L. Harmon
and N.F. Schrick. Evaluation of perennial ryegrass straw
as a forage source for ruminants. Journal of Animal Science
81(Suppl. 1):34. 2003.
Hanson, K.C.,
S.E. Kitts, N.B. Kristensen, D.E. Axe and D.L.
Harmon. Effects of feeding a slow-release urea
on ruminal nitrogen dynamics in steers. Journal of Animal
Science 81(Suppl. 1):265. 2003.
Bohnert, D.W.,
C.S. Schauer, S.J. Falck and D.L. Harmon.
Comparison of urea and soybean-meal as nitrogen supplements
to cool-season, low-quality forage: I. Daily and alternate
day supplementation effects on digestion and ruminal fermentation
in steers. Journal of Animal Science 81(Suppl. 1):92.
2003.
Experiment
Station Reports
Kristensen,
N.B. and D.L. Harmon. Metabolism of volatile
fatty acids absorbed from the washed rumen of steers.
2004 Beef Research Report. KY Agr. Report SR-2004-2. pp.
27. 2004.
Refereed
Journal Articles
Bertram, H.C.,
N.B. Kristensen, A. Maldendal, N.C. Nielsen, R. Bro, H.J.
Andersen and D.L. Harmon. A metabolomic
investigation of splanchnic metabolism using 1H NMR spectroscopy
of bovine plasma. Analytica Chimica Acta 536:1-6. 2005.
Other
Refereed Journal Articles
Yamka, R.M.,
S.E. Kitts and D.L. Harmon. Evaluation
of low-oligosaccharide low-phytate whole soybeans in canine
foods. Animal Feed Science Technology 120:79-91. 2005.
Yamka, R.M.,
B.M. Hetzler and D.L. Harmon. Evaluation
of low-oligosaccharide low-phytate whole soybeans and
soybean meal in canine foods. Journal of Animal Science
83:393-399. 2005.
Kristensen,
N.B. and D.L. Harmon. Effect of adding
valerate, caproate, and heptanoate to ruminal buffers
on splanchnic metabolism in steers under washed-rumen
conditions. Journal of Animal Science 83:1899-1907. 2005.
Bertram, H.C.,
N.B. Kristensen, A. Maldendal, N.C. Nielsen, R. Bro, H.J.
Andersen and D.L. Harmon. A metabolomic
investigation of splanchnic metabolism using 1H NMR spectroscopy
of bovine plasma. Analytica Chimica Acta 536:1-6. 2005.
Swanson, K.C.,
J.A. Benson, J.C. Matthews, and D.L. Harmon.
Pancreatic exocrine secretion and plasma concentration
of some gastrointestinal hormones in response to abomasal
infusion of starch hydrolysate and/or casein. Journal
of Animal Science 82:1781-1787. 2004.
Benson, J.A.,
K.C. Swanson, J.C. Matthews, and D.L. Harmon.
Influence of Starch Hydrolysate and/or Casein on Pancreatic
Exocrine Secretion and Plasma Hormone Concentrations in
Beef Steers. Journal of Animal Science 82:1781-1787. 2004.
Bertram, N.B.
Kristensen, A. Malmendal, N.C. Nielsen, S. K. Jemsern,
and D.L. Harmon. Use of NMR-based metabolomics
to assess metabolism in splanchnic tissues of steers.
Journal of Animal Feed Science 13: (Suppl. 1) 295-298.
2004.
Fisher, M.J.,
D.W. Bohnert, C.J. Ackerman, C.S. Schauer, T. DelCurto,
A.M. Craig, E.S. Vanzant, D.L. Harmon,
and N.F. Schrick. Evaluation of perennial ryegrass straw
as a forage source for ruminants. Journal of Animal Science
82:2175-2184. 2004.
Harmon,
D.L., R.M. Yamka, and N. Elam. Factors affecting
intestinal starch digestion in cattle. Can. Journal of
Animal Science 84:309-318. 2004.
Kristensen,
N.B. and D.L. Harmon. Splanchnic metabolism
of VFA absorbed from the washed reticulorumen of steers.
Journal of Animal Science 82:2033-2042. 2004.
Kristensen,
N.B. and D.L. Harmon. Effect of increasing
ruminal butyrate absorption on splanchnic metabolism of
VFA absorbed from the washed reticulorumen of steers.
Journal of Animal Science 82:3549-3559. 2004.
Raun, B.M.L.,
N.B. Kristensen, and D.L. Harmon. Splanchnic
metabolism of propylene infused into the jugular vein
of steers under washed rumen conditions. Journal of Animal
Feed Science 13: (Suppl. 1) 331-334. 2004.
Rodriguez,
S.M., K.C. Guimaraes, J.C. Matthews, K.R. McLeod, R.L.
Baldwin VI, and D.L. Harmon. Influence
of abomasal carbohydrates on small intestinal sodium-dependent
glucose co-transporter activity and abundance in steers.
Journal of Animal Science 82:3015-3023. 2004.
Yamka, R.M.,
S.E. Kitts, A.D. True, and D.L. Harmon.
Evaluation of corn gluten meal as a protein source in
canine foods. Animal Feed Science Technology 116:239-248.
2004.
Experiment
Station Reports & Bulletins
Hanson, K.C.,
K.R. McLeod, and D.L. Harmon. Effect
of supplemental energy source on performance of growing
beef heifers fed drought-damaged corn silage. 2004 Beef
Research Report. KY Agr. Report SR-2004-2. pp. 8. 2004.
Hanson, K.C.,
K.R. McLeod, J. Tricarico, and D.L. Harmon.
Effect of exogenous amylase and corn type on performance
and characteristics of finishing beef heifers. 2004 Beef
Research Report. KY Agr. Report SR-2004-2. pp. 22. 2004.
Hanson, K.C.,
S.E. Kitts, D.L. Harmon, and D.E. Axe.
Influence of Bufferfos®on the ruminal environment
of steers fed high-grin diets. 2004 Beef Research Report.
KY Agr. Report SR-2004-2. pp. 25. 2004.
Harmon,
D.L., K.C. Hanson, S.E. Kitts, N.B. Kristensen,
K.R. McLeod, and D.E. Axe. Influence of slow-release urea
on digestion and metabolism of ruminants. 2004 Beef Research
Report. KY Agr. Report SR-2004-2. pp. 29. 2004.
Kitts, S.E.,
K.C. Hanson, N.A. Elam, M.C. Newman, D.L. Harmon,
and K.R. McLeod. Effects of corn type and forage level
on growth performance and E.Coli shedding in finishing
beef steers. 2004 Beef Research Report. KY Agr. Report
SR-2004-2. pp. 9. 2004.
Kristensen,
N.B. and D.L. Harmon. Metabolism of volatile
fatty acids absorbed from the washed rumen of steers.
2004 Beef Research Report. KY Agr. Report SR-2004-2. pp.
27. 2004.
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